Drugs That Lower Plasma Cholesterol, Lipids and Triglycerides, Their Mechanisms and Therapeutic Uses

Dietary or pharmacological reduction of elevated plasma cholesterol levels can reduce the risk of atherosclerosis and subsequent cardiovascular disease.
the association between elevated plasma triglyceride levels is less dramatic, but it is becoming more recognized. In addition, elevated plasma Triglycerides can produce life-threatening pancreatitis.

Drugs useful in treating hyperlipidemias ( Increased conc. of lipids in the blood)

1. Inhibitors of Cholesterol Biosynthesis.
following drugs inhibit cholesterol synthesis:

Drugs that inhibit cholesterol synthesis are effective at lowering plasma LDL cholesterol and total cholesterol

2. Nicotinic acid ( Niacin ) (brand names: Nicobid, Nicolar)

Nicotinic acid

Fibric Acid Analogues.
Finofibrate ( Antara, Triglide, Lofibra)

Gemfibrozil (Lopid)

Bile acid Absorption Inhibitors

Ezetimibe (Zetia)

Bile acid sequestrants

these agents include
cholestyramine (Questran),
Colestipol (Colestid)
colesevelam (WelChol)

Cryoglobulinemia, Cryoglobulinemia Causes, Symptoms & Treatment

Cryoglobulinemia causes Hep C Myeloma, Waldenstrom’s macroglobulinemia, SLE, Rheumatoid arthritis, Sjogren’s syndrome, Symptoms, Immunoglobulins precipitate when cooled under skin, ulcers, rashes, gangrene, Raynaud’s phenomenon. Treatment. Plasma exchange, Chemotherapy, Treat the cause.

Human Parasites, Types of Parasites, and Classification

Parasite: A parasite is a living organism which gets nutrition and protection from another organism where it lives. Parasites enter into the human body through mouth, skin and genitalia. In this article, we will generally discuss the types and classification of parasites. It is important from an academic point of view. Those parasites are harmful, which derives their nutrition and other benefits from the host and host get nothing in return but suffers from some injury. Types of Parasites Ecto-parasite: An ectoparasite lives outside on the surface of the body of the host. Endo-parasite: An endo-parasite lives inside the body of the host, it lives in the blood, tissues, body cavities, digestive tract or other organs. Temporary parasite: A temporary parasite visits its host for a short period of time. Permanent parasite: Permanent parasite lives its whole life in the host. Facultative parasite: A facultative parasite can live both independently and dependently. It lives in the

How to taper off, wean off beta blocker, atenolol, Propranolol, Metoprolol

Beta blockers include, atenolol (Tenormin), propranolol (Inderal ) and metoprolol (Lopressor) and are used to treat high blood pressure, certain cardiac problems, migraine and few other conditions. People usually take atenolol, propranolol or metoprolol for many years as a treatment of high blood pressure or after having an episode of heart attack . Sometimes, it becomes necessary to withdraw these beta blockers due to their potential side effects that trouble the patients or sometimes doctor wants to change the drug and shift the patient to some other anti-hypertensive medicine. No matter whatever the cause is, whenever, a patient who has been using a beta blocker for a long period of time, and he needs to be stopped from further usage of that beta blocker, must not stop taking it. One should taper off the dose of a beta blocker. Now a question arises how to wean off or taper off a beta blocker? The method of tapering off beta blocker varies from individual to individual. Allow you

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